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iGMDRD638

Canonical SMILES: CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5

InChI: InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)

InChI Key: RHXHGRAEPCAFML-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	DRUGBANK ID	Drug Status	Drug Type
Ribociclib	CHEMBL3707266 CHEMBL3545110	44631900	DB11730	Alone	Small Molecule

Drug Class:

Amines Antineoplastic Agents Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Heterocyclic Compounds, 2-Ring Kinase Inhibitor Pyridines

Drug Targets:

CDK4 (P11802)CDK6 (Q00534)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
1021	CDK6	15
1019	CDK4	18
5290	PIK3CA	1
4893	NRAS	3

Gene in drug-gene network: Network Plot

Models in Ribociclib

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.