iGMDRD714

Canonical SMILES: CN(C)CC(=O)N[C@@H]1CC[C@@H](CCNC(=O)Nc2ccc(F)cc2)O[C@H]1CO

InChI: InChI=1S/C19H29FN4O4/c1-24(2)11-18(26)23-16-8-7-15(28-17(16)12-25)9-10-21-19(27)22-14-5-3-13(20)4-6-14/h3-6,15-17,25H,7-12H2,1-2H3,(H,23,26)(H2,21,22,27)/t15-,16+,17-/m0/s1

InChI Key: HVYAXUQBEQKNPC-BBWFWOEESA-N

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Standard Name
Pubchem CID
Drug Status
Standard NameBRD-K17060750
Pubchem CID54639700
Drug StatusAlone

Drug-model tissue-cancer distribution: Bubble Plot

OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: undefined model num: 1LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Drug-gene pathway enrichments

1kegg: Longevity regulating pathway - Homo sapiens (human)1kegg: Apoptosis - multiple species - Homo sapiens (human)1kegg: Apoptosis - Homo sapiens (human)1kegg: Protein processing in endoplasmic reticulum - Homo sapiens (human)1kegg: p53 signaling pathway - Homo sapiens (human)1kegg: Necroptosis - Homo sapiens (human)1kegg: Neurotrophin signaling pathway - Homo sapiens (human)1kegg: Huntington,s disease - Homo sapiens (human)1kegg: Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human)1kegg: AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)

Drug-gene GO enrichments

3BP: positive regulation of apoptotic process3BP: apoptotic process3MF: protein homodimerization activity2MF: GTPase activity2CC: cytosol2CC: mitochondrial outer membrane2BP: release of cytochrome c from mitochondria2BP: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2BP: activation of cysteine-type endopeptidase activity involved in apoptotic process2MF: protein binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
57111 RAB25 1
581 BAX 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in BRD-K17060750

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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