iGMDRD724

Canonical SMILES: COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl

InChI: InChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30)

InChI Key: GCYIGMXOIWJGBU-UHFFFAOYSA-N

Loading, please wait...
Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameAZD3463
Pubchem CID56599300
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

1wikipathways: Differentiation Pathway1wikipathways: MET in type 1 papillary renal cell carcinoma1kegg: Non-small cell lung cancer - Homo sapiens (human)1kegg: Pathways in cancer - Homo sapiens (human)1wikipathways: NAD metabolism, sirtuins and aging1wikipathways: Spinal Cord Injury

Drug-gene GO enrichments

5MF: transmembrane receptor protein tyrosine kinase activity4MF: protein tyrosine kinase activity4CC: integral component of plasma membrane3BP: cell differentiation2BP: phosphorylation2BP: positive regulation of protein phosphorylation2BP: negative regulation of apoptotic process2BP: protein autophosphorylation2BP: multicellular organism development2BP: negative regulation of signal transduction

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
238 ALK 1
6098 ROS1 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in AZD3463

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.