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iGMDRD763

Canonical SMILES: CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC

InChI: InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)

InChI Key: DUYJMQONPNNFPI-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	DRUGBANK ID	Drug Status	Drug Type
Osimertinib	CHEMBL3545063 CHEMBL3353410	71496500	DB09330	Alone	Small Molecule

Drug Class:

Acids, Acyclic Acrylates Amides Amines Antineoplastic Agents BCRP/ABCG2 Substrates Carboxylic Acids Cytochrome P-450 Enzyme Inducers Enzyme Inhibitors Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Kinase Inhibitor P-glycoprotein/ABCB1 Substrates Protein Kinase Inhibitors

Drug Targets:

EGFR (P00533)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
2064	ERBB2	1
8731	RNMT	1
1956	EGFR	16

Gene in drug-gene network: Network Plot

Models in Osimertinib

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.