iGMDRD867

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Standard Name
Drug Status
Standard NameBRD1835
Drug StatusAlone

Drug Targets:

EZH2

Drug-model tissue-cancer distribution: Bubble Plot

UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: undefined model num: 1LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Drug-gene pathway enrichments

1reactome: RNA Polymerase II Transcription1reactome: Gene expression (Transcription)1reactome: Chromatin organization1reactome: Chromatin modifying enzymes1reactome: Generic Transcription Pathway1reactome: RMTs methylate histone arginines1reactome: Transcriptional regulation by RUNX11reactome: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known1kegg: Thermogenesis - Homo sapiens (human)1kegg: Hepatocellular carcinoma - Homo sapiens (human)

Drug-gene GO enrichments

3MF: protein binding2CC: nucleoplasm2CC: nucleus2BP: nucleosome disassembly2BP: chromatin remodeling2BP: positive regulation of transcription of nucleolar large rRNA by RNA polymerase I2BP: ATP-dependent chromatin remodeling2BP: regulation of transcription by RNA polymerase II2MF: transcription coactivator activity2CC: SWI/SNF complex

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
6598 SMARCB1 1
5834 PYGB 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in BRD1835

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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