iGMDRD869

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Standard Name
Drug Status
Standard NameBRD55319
Drug StatusAlone

Drug Targets:

SIRT1

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 3undefinedtissue: undefined cancer: SMALL_CELL_CARCINOMA model num: 1

Drug-gene pathway enrichments

2kegg: Non-small cell lung cancer - Homo sapiens (human)1pid: Coregulation of Androgen receptor activity1pid: AP-1 transcription factor network1wikipathways: DNA Damage Response (only ATM dependent)1wikipathways: Senescence and Autophagy in Cancer1pid: Regulation of nuclear beta catenin signaling and target gene transcription1pid: C-MYB transcription factor network1pid: FOXM1 transcription factor network1pid: E2F transcription factor network1pid: Validated transcriptional targets of deltaNp63 isoforms

Drug-gene GO enrichments

3CC: cytosol2MF: protein binding2BP: cell cycle arrest2CC: nucleus2MF: cyclin-dependent protein serine/threonine kinase inhibitor activity2BP: negative regulation of cell proliferation2MF: Rac guanyl-nucleotide exchange factor activity2CC: cytoplasm2BP: G-protein coupled receptor signaling pathway2CC: plasma membrane

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
80243 PREX2 1
2272 FHIT 1
1029 CDKN2A 2
Showing 1 to 3 of 3 rows

Gene in drug-gene network: Network Plot

Models in BRD55319

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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