iGMDRD880

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Standard Name
Drug Status
Drug Type
Standard Namechemotherapy (HER2 ampl)
Drug StatusClassification
Drug TypeTherapy

Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Breast Carcinoma model num: 2

Drug-gene pathway enrichments

3reactome: Signal Transduction3reactome: Immune System2wikipathways: Androgen Receptor Network in Prostate Cancer2wikipathways: Signaling Pathways in Glioblastoma2wikipathways: Focal Adhesion2wikipathways: Signaling of Hepatocyte Growth Factor Receptor2wikipathways: Regulation of Microtubule Cytoskeleton2wikipathways: Copper homeostasis2reactome: PIP3 activates AKT signaling2reactome: PI Metabolism

Drug-gene GO enrichments

3CC: cytoplasm3CC: cytosol3MF: 1-phosphatidylinositol-3-kinase activity2BP: negative regulation of cell proliferation2BP: endothelial cell migration2CC: nucleoplasm2BP: phosphatidylinositol-mediated signaling2BP: negative regulation of phosphatidylinositol 3-kinase signaling2BP: negative regulation of protein kinase B signaling2BP: protein dephosphorylation

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
5290 PIK3CA 1
5728 PTEN 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in chemotherapy (HER2 ampl)

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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