iGMDRD9

Canonical SMILES: C1=CC=C2C(=C1)C(=O)C3=C(C=CC(=C3O2)CN4C=CN=C4)[N+](=O)[O-]

InChI: InChI=1S/C17H11N3O4/c21-16-12-3-1-2-4-14(12)24-17-11(9-19-8-7-18-10-19)5-6-13(15(16)17)20(22)23/h1-8,10H,9H2

InChI Key: JLTNBMDVMUSXHQ-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameAromatase ihibitor
Pubchem CID2238
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Invasive Breast Carcinoma (BRCA) model num: 1BREASTtissue: BREAST cancer: Breast Carcinoma model num: 2

Drug-gene pathway enrichments

3reactome: RNA Polymerase II Transcription3reactome: Gene expression (Transcription)3reactome: Generic Transcription Pathway2reactome: Signal Transduction2reactome: Post-translational protein modification2reactome: Metabolism of proteins2reactome: Transcriptional regulation by RUNX12reactome: Regulation of RUNX2 expression and activity2reactome: Transcriptional regulation by RUNX22reactome: Estrogen-dependent gene expression

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2625 GATA3 2
2099 ESR1 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in Aromatase ihibitor

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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