iGMDRD941


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Standard Name
Drug Status
Standard NameMEDI0680
Drug StatusAlone

Drug-model tissue-cancer distribution: Bubble Plot

BLADDEtissue: BLADDE cancer: BLADDER model num: 0BLADDERtissue: BLADDER cancer: Urethral Urothelial Carcinoma (UCU) model num: 2

Drug-gene pathway enrichments

3reactome: DNA Repair3reactome: Mismatch Repair2kegg: Mismatch repair - Homo sapiens (human)2wikipathways: Mismatch repair2kegg: Colorectal cancer - Homo sapiens (human)2reactome: Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)2wikipathways: Chromosomal and microsatellite instability in colorectal cancer2reactome: Disease2kegg: Pathways in cancer - Homo sapiens (human)2reactome: Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)

Drug-gene GO enrichments

9BP: mismatch repair5MF: guanine/thymine mispair binding5MF: mismatched DNA binding4MF: single thymine insertion binding4BP: maintenance of DNA repeat elements4MF: MutLalpha complex binding4MF: ADP binding4CC: MutSalpha complex4BP: determination of adult lifespan4MF: four-way junction DNA binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2956 MSH6 1
4436 MSH2 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in MEDI0680

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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