iGMDRD942

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Standard Name
DRUGBANK ID
Drug Status
Standard NameMEDI4736
DRUGBANK IDDB11714
Drug StatusAlone

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

3reactome: Mismatch Repair3reactome: DNA Repair2reactome: Disease2kegg: Pathways in cancer - Homo sapiens (human)2kegg: Mismatch repair - Homo sapiens (human)2wikipathways: Chromosomal and microsatellite instability in colorectal cancer2wikipathways: Mismatch repair2kegg: Colorectal cancer - Homo sapiens (human)2reactome: Defective Mismatch Repair Associated With MSH62reactome: Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)

Drug-gene GO enrichments

9BP: mismatch repair5MF: guanine/thymine mispair binding5MF: mismatched DNA binding4BP: isotype switching4BP: negative regulation of DNA recombination4MF: ADP binding4BP: determination of adult lifespan4MF: MutLalpha complex binding4MF: ATP binding4MF: single thymine insertion binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2956 MSH6 1
4436 MSH2 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in MEDI4736

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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