iGMDRD968

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Standard Name
Drug Status
Drug Type
Standard NamePan-RAF inhibitor
Drug StatusFamily
Drug Typeundefined

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

7reactome: Signal Transduction6reactome: Signaling by Receptor Tyrosine Kinases5reactome: Signalling to ERKs5reactome: Signaling by NTRKs5reactome: Signaling by NTRK1 (TRKA)4wikipathways: MAPK Signaling Pathway4reactome: Signaling by ERBB24reactome: RAF/MAP kinase cascade4kegg: MAPK signaling pathway - Homo sapiens (human)4reactome: Disease

Drug-gene GO enrichments

6BP: MAPK cascade5CC: cytosol4CC: plasma membrane4MF: protein binding3BP: Ras protein signal transduction3BP: positive regulation of GTPase activity3CC: membrane2BP: regulation of synaptic transmission, GABAergic2BP: negative regulation of MAPK cascade2BP: forebrain astrocyte development

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 4
673 BRAF 10
4893 NRAS 2
4763 NF1 2
Showing 1 to 4 of 4 rows

Gene in drug-gene network: Network Plot

Models in Pan-RAF inhibitor

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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