iGMDRD984

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Standard Name
Drug Status
Drug Type
Standard NamePI3K pathway inhibitor (alone or in combination)
Drug StatusFamily/Alone/Combination
Drug Typeundefined

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: Lung Cancer model num: 5BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: Colorectal Adenocarcinoma (COADREAD) model num: 3BOWELtissue: BOWEL cancer: Colorectal Cancer model num: 2BRAItissue: BRAI cancer: BRAIN model num: 0BRAINtissue: BRAIN cancer: Glioma model num: 3

Drug-gene pathway enrichments

3reactome: Signal Transduction3reactome: Immune System2kegg: Sphingolipid signaling pathway - Homo sapiens (human)2kegg: Phosphatidylinositol signaling system - Homo sapiens (human)2kegg: FoxO signaling pathway - Homo sapiens (human)2kegg: Inositol phosphate metabolism - Homo sapiens (human)2kegg: Autophagy - animal - Homo sapiens (human)2kegg: mTOR signaling pathway - Homo sapiens (human)2kegg: Cellular senescence - Homo sapiens (human)2kegg: PI3K-Akt signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

3MF: 1-phosphatidylinositol-3-kinase activity3CC: cytosol3CC: cytoplasm2BP: endothelial cell migration2BP: phosphatidylinositol dephosphorylation2BP: protein kinase B signaling2BP: phosphatidylinositol-mediated signaling2BP: cell migration2BP: phosphatidylinositol phosphorylation2BP: phosphatidylinositol-3-phosphate biosynthetic process

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
5290 PIK3CA 9
5728 PTEN 4
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Gene in drug-gene network: Network Plot

Models in PI3K pathway inhibitor (alone or in combination)

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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