TACSTD2
Summary: This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| tumor associated calcium signal transducer 2 | MIM:137290 | Ensembl:ENSG00000184292 | HGNC:HGNC:11530 | PA36305 | 1p32.1 |
GO terms in TACSTD2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | TAS | GO:0038023 | signaling receptor activity |
| MF | IBA | GO:0098641 | cadherin binding involved in cell-cell adhesion |
| BP | TAS | GO:0007166 | cell surface receptor signaling pathway |
| BP | IEA | GO:0007601 | visual perception |
| BP | TAS | GO:0008283 | cell proliferation |
| BP | ISS | GO:0010633 | negative regulation of epithelial cell migration |
| BP | IEA | GO:0050678 | regulation of epithelial cell proliferation |
| BP | ISS | GO:0051497 | negative regulation of stress fiber assembly |
| BP | IEA | GO:0060675 | ureteric bud morphogenesis |
| BP | ISS | GO:0090191 | negative regulation of branching involved in ureteric bud morphogenesis |
| BP | ISS | GO:1900025 | negative regulation of substrate adhesion-dependent cell spreading |
| BP | ISS | GO:1900028 | negative regulation of ruffle assembly |
| BP | ISS | GO:2000146 | negative regulation of cell motility |
| BP | IBA | GO:2000738 | positive regulation of stem cell differentiation |
| CC | IBA | GO:0005615 | extracellular space |
| CC | IBA | GO:0005634 | nucleus |
| CC | TAS | GO:0005829 | cytosol |
| CC | TAS | GO:0005887 | integral component of plasma membrane |
| CC | IBA | GO:0005923 | bicellular tight junction |
| CC | ISS | GO:0009925 | basal plasma membrane |
| CC | TAS | GO:0016020 | membrane |
| CC | ISS | GO:0016328 | lateral plasma membrane |
| CC | HDA | GO:0070062 | extracellular exosome |
Gene expression in normal tissue: TACSTD2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TACSTD2
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TACSTD2
CLASSFICATION
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