CUL2

Summary:

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namecullin 2
OMIM IDMIM:603135
Ensembl IDEnsembl:ENSG00000108094
HGNC IDHGNC:HGNC:2552
PHARMGKB IDPA27048
Map Location10p11.21

Gene Categories:

TUMOR SUPPRESSOR

GO terms in CUL2


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
BP TAS GO:0000082 G1/S transition of mitotic cell cycle
BP IEA GO:0006511 ubiquitin-dependent protein catabolic process
BP TAS GO:0007050 cell cycle arrest
BP TAS GO:0008285 negative regulation of cell proliferation
BP IEA GO:0016032 viral process
BP IEA GO:0016567 protein ubiquitination
Showing 1 to 6 of 22 rows rows per page

Gene expression in normal tissue: CUL2

Gene-model tissue-cancer distribution: Bubble Plot

BRAItissue: BRAI cancer: BRAIN model num: 0BRAINtissue: BRAIN cancer: Low-Grade Glioma, NOS (LGGNOS) model num: 2LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: Lung Adenocarcinoma (LUAD) model num: 3

Gene-drug pathway distribution

PI3K/MTOR signaling1Cytoskeleton1ERK MAPK signaling1Genome integrity1Protein stability and degradation1

Pathways in CUL2


Loading, please wait...
Database
Pathway ID
Pathway Des.
reactome R-HSA-1234174 Regulation of Hypoxia-inducible Factor (HIF) by oxygen
reactome R-HSA-1234174 Regulation of Hypoxia-inducible Factor (HIF) by oxygen
reactome R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
reactome R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1280218 Adaptive Immune System
Showing 1 to 6 of 27 rows rows per page

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD309 17AAG 1
iGMDRD262 KU-55933 1
iGMDRD399 Selumetinib 1
iGMDRD347 Y-39983 1
Showing 1 to 4 of 5 rows

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CUL2

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.