iGMDRD507

Canonical SMILES: CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N

InChI: InChI=1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13-/m0/s1

InChI Key: KGPGFQWBCSZGEL-ZDUSSCGKSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
GSK690693CHEMBL494089 16725700DB12745AloneSmall Molecule


Drug Targets:

AKT

Drug Pathways:

PI3K/MTOR signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
6926TBX31
2033EP3001
7307U2AF11
6416MAP2K41
1029CDKN2A1
23019CNOT12
8731RNMT1
5290PIK3CA5
1956EGFR1
3553IL1B1
5728PTEN5
8453CUL21
6146RPL221
10735STAG21
196528ARID21
5925RB11
4893NRAS1
7040TGFB11

Gene in drug-gene network: Network Plot

Models in GSK690693

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