TNS4
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| tensin 4 | MIM:608385 | Ensembl:ENSG00000131746 | HGNC:HGNC:24352 | PA142670717 | 17q21.2 |
GO terms in TNS4
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0003779 | actin binding |
| MF | IPI | GO:0005515 | protein binding |
| CC | TAS | GO:0005829 | cytosol |
| CC | IEA | GO:0005856 | cytoskeleton |
| CC | IDA | GO:0005925 | focal adhesion |
| BP | IEA | GO:0006915 | apoptotic process |
| BP | IDA | GO:0008104 | protein localization |
Gene expression in normal tissue: TNS4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TNS4
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2880 | Glucocorticoid Receptor Pathway |
| wikipathways | WP2882 | Nuclear Receptors Meta-Pathway |
| netpath | Pathway_EGFR1 | EGFR1 |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-6806834 | Signaling by MET |
| reactome | R-HSA-8875513 | MET interacts with TNS proteins |
| reactome | R-HSA-8875878 | MET promotes cell motility |
| reactome | R-HSA-9006934 | Signaling by Receptor Tyrosine Kinases |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD133 | Lapatinib | 1 |
| iGMDRD353 | PD0325901 | 1 |
| iGMDRD131 | Erlotinib | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TNS4
CLASSFICATION
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