ADGRV1


Summary: This gene encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
adhesion G protein-coupled receptor V1MIM:602851Ensembl:ENSG00000164199HGNC:HGNC:17416PA1349607795q14.3

GO terms in ADGRV1


Term TypeEvidence TypeGO Term IDGO Des.
MFNASGO:0004930G-protein coupled receptor activity
MFIDAGO:0005509calcium ion binding
MFIPIGO:0005515protein binding
BPIEAGO:0007166cell surface receptor signaling pathway
BPIEAGO:0007186G-protein coupled receptor signaling pathway
BPNASGO:0007399nervous system development
BPIEAGO:0007601visual perception
BPIMPGO:0007605sensory perception of sound
BPIMPGO:0045494photoreceptor cell maintenance
BPIMPGO:0048496maintenance of animal organ identity
BPIMPGO:0050877nervous system process
BPIMPGO:0050953sensory perception of light stimulus
BPNASGO:0098609cell-cell adhesion
CCIDAGO:0005737cytoplasm
CCIEAGO:0005886plasma membrane
CCIDAGO:0009986cell surface
CCNASGO:0016020membrane
CCIEAGO:0016021integral component of membrane
CCIEAGO:0032420stereocilium
CCIDAGO:0043235receptor complex
CCIEAGO:0045202synapse
CCHDAGO:0070062extracellular exosome

Gene expression in normal tissue: ADGRV1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ADGRV1


DatabasePathway IDPathway Des.
wikipathwaysWP117GPCRs, Other

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD748PHA-6657521
iGMDRD399Selumetinib1
iGMDRD353PD03259011
iGMDRD30917AAG1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ADGRV1

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