RIPK4
Summary: The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:605706 Ensembl IDEnsembl:ENSG00000183421 HGNC IDHGNC:HGNC:496 PHARMGKB IDPA24805 Map Location21q22.3 |
GO terms in RIPK4
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IMP | GO:0002009 | morphogenesis of an epithelium |
BP | IEA | GO:0006468 | protein phosphorylation |
BP | IMP | GO:0051092 | positive regulation of NF-kappaB transcription factor activity |
CC | ISS | GO:0005737 | cytoplasm |
CC | IEA | GO:0016020 | membrane |
MF | IEA | GO:0004674 | protein serine/threonine kinase activity |
Gene expression in normal tissue: RIPK4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RIPK4
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RIPK4
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |