TACSTD2


Summary: This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
tumor associated calcium signal transducer 2MIM:137290Ensembl:ENSG00000184292HGNC:HGNC:11530PA363051p32.1

GO terms in TACSTD2


Term TypeEvidence TypeGO Term IDGO Des.
MFIPIGO:0005515protein binding
MFTASGO:0038023signaling receptor activity
MFIBAGO:0098641cadherin binding involved in cell-cell adhesion
BPTASGO:0007166cell surface receptor signaling pathway
BPIEAGO:0007601visual perception
BPTASGO:0008283cell proliferation
BPISSGO:0010633negative regulation of epithelial cell migration
BPIEAGO:0050678regulation of epithelial cell proliferation
BPISSGO:0051497negative regulation of stress fiber assembly
BPIEAGO:0060675ureteric bud morphogenesis
BPISSGO:0090191negative regulation of branching involved in ureteric bud morphogenesis
BPISSGO:1900025negative regulation of substrate adhesion-dependent cell spreading
BPISSGO:1900028negative regulation of ruffle assembly
BPISSGO:2000146negative regulation of cell motility
BPIBAGO:2000738positive regulation of stem cell differentiation
CCIBAGO:0005615extracellular space
CCIBAGO:0005634nucleus
CCTASGO:0005829cytosol
CCTASGO:0005887integral component of plasma membrane
CCIBAGO:0005923bicellular tight junction
CCISSGO:0009925basal plasma membrane
CCTASGO:0016020membrane
CCISSGO:0016328lateral plasma membrane
CCHDAGO:0070062extracellular exosome

Gene expression in normal tissue: TACSTD2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TACSTD2


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD133Lapatinib2
iGMDRD131Erlotinib2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TACSTD2

​​​​