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iGMDRD83

Canonical SMILES: CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)O

InChI: InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1

InChI Key: GAGWJHPBXLXJQN-UORFTKCHSA-N

Standard Name	CHEMBL	Pubchem CID	KEGG Drug ID	DRUGBANK ID	Drug Status	Drug targets (TTD)	Drug Type
Capecitabine	CHEMBL1773	60953	D01223	DB01101	Alone	DAP000761	Small Molecule

Drug Class:

Antimetabolites Antimetabolites, Antineoplastic Antineoplastic Agents Antineoplastic and Immunomodulating Agents Carbohydrates Cardiotoxic antineoplastic agents Cytidine Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (strong)Cytochrome P-450 Enzyme Inhibitors Deoxycytidine Deoxyribonucleosides Fluoropyrimidines Fluorouracil Glycosides Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Immunosuppressive Agents Myelosuppressive Agents Noxae Nucleic Acids, Nucleotides, and Nucleosides Nucleoside Metabolic Inhibitor Nucleosides Pyrimidine Analogues Pyrimidine Nucleosides Pyrimidines Pyrimidinones Ribonucleosides Toxic Actions Uracil

Drug Targets:

TYMS (P04818)DNA RNA

Drug Pathways:

Pyrimidine metabolism One carbon pool by folate Drug metabolism - other enzymes

Drug Synonyms:

Capecitabine (JAN/USAN/INN)Xeloda (TN)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
2064	ERBB2	3
7157	TP53	1
673	BRAF	1
1806	DPYD	7

Gene in drug-gene network: Network Plot

Models in Capecitabine

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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.