iGMDRD206

Canonical SMILES: CCOC1=C(C(=CC(=C1)C=C2C(=NN(C2=O)C3=CC=CC=C3)C)Cl)OCC(=O)OC

InChI: InChI=1S/C22H21ClN2O5/c1-4-29-19-12-15(11-18(23)21(19)30-13-20(26)28-3)10-17-14(2)24-25(22(17)27)16-8-6-5-7-9-16/h5-12H,4,13H2,1-3H3/b17-10+

InChI Key: RKKFQJXGAQWHBZ-LICLKQGHSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameSJ-172550
Pubchem CID1317460
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: undefined model num: 2LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Drug-gene pathway enrichments

3reactome: Signal Transduction3reactome: Signaling by Receptor Tyrosine Kinases3reactome: Immune System2reactome: IRS-related events triggered by IGF1R2reactome: G2/M Checkpoints2reactome: G2/M DNA damage checkpoint2wikipathways: Brain-Derived Neurotrophic Factor (BDNF) signaling pathway2reactome: Ubiquitin Mediated Degradation of Phosphorylated Cdc25A2reactome: G1/S DNA Damage Checkpoints2reactome: p53-Independent G1/S DNA damage checkpoint

Drug-gene GO enrichments

7CC: cytosol7CC: nucleus6CC: cytoplasm5CC: plasma membrane4BP: insulin receptor signaling pathway4MF: protein binding3MF: protein serine/threonine kinase activity3BP: cellular response to oxidative stress3MF: phosphatidylinositol 3-kinase binding3MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
1111 CHEK1 1
3667 IRS1 1
1938 EEF2 1
4780 NFE2L2 2
Showing 1 to 4 of 4 rows

Gene in drug-gene network: Network Plot

Models in SJ-172550

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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