iGMDRD222

Canonical SMILES: CC1=C(C=C(N1CCCN2CCOCC2)C3=CC=CC=C3)C(=O)NC4=CC=CC(=C4)C(F)(F)F

InChI: InChI=1S/C26H28F3N3O2/c1-19-23(25(33)30-22-10-5-9-21(17-22)26(27,28)29)18-24(20-7-3-2-4-8-20)32(19)12-6-11-31-13-15-34-16-14-31/h2-5,7-10,17-18H,6,11-16H2,1H3,(H,30,33)

InChI Key: NCZYSQOTAYFTNM-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameHC-067047
Pubchem CID2742550
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: undefined model num: 1SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: undefined model num: 1LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: undefined model num: 2undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Drug-gene pathway enrichments

2reactome: Pre-NOTCH Transcription and Translation2reactome: Pre-NOTCH Expression and Processing2reactome: Cell Cycle2reactome: Signal Transduction2reactome: G0 and Early G12reactome: Signaling by NOTCH2reactome: Generic Transcription Pathway2reactome: Activation of E2F1 target genes at G1/S2reactome: RNA Polymerase II Transcription2reactome: Gene expression (Transcription)

Drug-gene GO enrichments

4CC: nucleoplasm4MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding4CC: nucleus4MF: protein binding3MF: DNA binding2BP: positive regulation of transcription, DNA-templated2BP: negative regulation of transcription, DNA-templated2BP: nucleosome disassembly2CC: SWI/SNF complex2MF: transcription coactivator activity

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
6598 SMARCB1 1
7301 TYRO3 1
1869 E2F1 1
Showing 1 to 3 of 3 rows

Gene in drug-gene network: Network Plot

Models in HC-067047

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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