iGMDRD368

Canonical SMILES: O=CO[Pt]1(OC=O)[NH2]C2CCCCC2[NH2]1

InChI: InChI=1S/C6H14N2.2CH2O2.Pt/c7-5-3-1-2-4-6(5)8;2*2-1-3;/h5-6H,1-4,7-8H2;2*1H,(H,2,3);/q;;;+2/p-2

InChI Key: DRMCATBEKSVAPL-BNTLRKBRSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameOxaliplatin
Pubchem CID9887050
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: Colorectal Cancer model num: 5STOMACtissue: STOMAC cancer: STOMACH model num: 0STOMACHtissue: STOMACH cancer: Esophagogastric Carcinoma model num: 1

Drug-gene pathway enrichments

6reactome: Signal Transduction3reactome: Intracellular signaling by second messengers3pid: Direct p53 effectors3reactome: Gene expression (Transcription)3reactome: RNA Polymerase II Transcription3reactome: PIP3 activates AKT signaling3reactome: Generic Transcription Pathway3reactome: DNA Repair3reactome: Disease3kegg: Gastric cancer - Homo sapiens (human)

Drug-gene GO enrichments

7CC: nucleus7MF: protein binding7CC: cytosol7MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding7CC: nucleoplasm5BP: negative regulation of canonical Wnt signaling pathway5BP: positive regulation of transcription by RNA polymerase II5CC: cytoplasm5BP: positive regulation of gene expression4BP: negative regulation of transcription by RNA polymerase II

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2064 ERBB2 1
5460 POU5F1 1
7157 TP53 1
4292 MLH1 1
Showing 1 to 4 of 6 rows

Gene in drug-gene network: Network Plot

Models in Oxaliplatin

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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