iGMDRD376

Canonical SMILES: CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl

InChI: InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H,1-3H3,(H2,25,26,27,28)

InChI Key: SPMVMDHWKHCIDT-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameTivozanib
CHEMBLCHEMBL3426917 CHEMBL2105756 CHEMBL1289494
Pubchem CID9911830
DRUGBANK IDDB11800
Drug StatusAlone
Drug TypeSmall Molecule


Drug Targets:

VEGFRFLT1FLT3KDR

Drug Pathways:

RTK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 1
55252 ASXL2 1
4609 MYC 1
3553 IL1B 1
Showing 1 to 4 of 7 rows

Gene in drug-gene network: Network Plot

Models in Tivozanib

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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