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iGMDRD429

Canonical SMILES: C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6

InChI: InChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,24,32)

InChI Key: FOFDIMHVKGYHRU-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	DRUGBANK ID	Drug Status	Drug Type
Amuvatinib	CHEMBL2105685 CHEMBL2103851	11282300	DB12742	Alone	Small Molecule

Drug Class:

Heterocyclic Compounds Heterocyclic Compounds, 1-Ring

Drug Targets:

KIT (P10721)MET (P08581)RET (P07949)PDGFRA (P16234)FLT3 (P36888)RAD51 (Q06609)

Drug Pathways:

Other, kinases

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
7157	TP53	2
9223	MAGI1	1
4893	NRAS	1
55193	PBRM1	1

Gene in drug-gene network: Network Plot

Models in Amuvatinib

SITE

DATATYPES

CLASSFICATION

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