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iGMDRD487

Canonical SMILES: CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NC)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C

InChI: InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)

InChI Key: WXCXUHSOUPDCQV-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	DRUGBANK ID	Drug Status	Drug Type
Enzalutamide	CHEMBL1082407	15951500	DB08899	Alone	Small Molecule

Drug Class:

Androgen Antagonists Androgen Receptor Inhibitor Antiandrogens Antineoplastic Agents Antineoplastic and Immunomodulating Agents Azoles Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A Inducers (strong)Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strong)Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Endocrine Therapy Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Hormone Antagonists and Related Agents Hydantoins Imidazoles Imidazolidines Non-Steroidal Anti-Androgens P-glycoprotein/ABCB1 Inhibitors Thiohydantoins

Drug Targets:

AR (P10275)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
1586	CYP17A1	1
5728	PTEN	2
374	AREG	16

Gene in drug-gene network: Network Plot

Models in Enzalutamide

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.