iGMDRD488

Canonical SMILES: CC1CN(CC(O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C=CC=C4C3)C5=CC(=O)C=C(O5)N6CCOCC6

InChI: InChI=1S/C30H33N3O5S/c1-19-16-32(17-20(2)37-19)18-28(35)31-23-6-7-27-22(13-23)12-21-4-3-5-25(30(21)39-27)26-14-24(34)15-29(38-26)33-8-10-36-11-9-33/h3-7,13-15,19-20H,8-12,16-18H2,1-2H3,(H,31,35)/t19-,20+

InChI Key: SCELLOWTHJGVIC-BGYRXZFFSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameKU-60019
Pubchem CID15953900
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

2reactome: G0 and Early G12reactome: Signaling by NOTCH2reactome: Signal Transduction2reactome: Transcription of E2F targets under negative control by DREAM complex2wikipathways: miR-targeted genes in lymphocytes - TarBase2pid: Direct p53 effectors2wikipathways: miR-targeted genes in muscle cell - TarBase2reactome: Cell Cycle2reactome: Pre-NOTCH Transcription and Translation2reactome: G1/S-Specific Transcription

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
4170 MCL1 1
54658 UGT1A1 1
1869 E2F1 1
Showing 1 to 3 of 3 rows

Gene in drug-gene network: Network Plot

Models in KU-60019

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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