iGMDRD500


Canonical SMILES: C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O

InChI: InChI=1S/C21H21F3IN3O2/c22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/h4-7,9,17,26-27,30H,1-3,8,10-11H2/t17-/m0/s1

InChI Key: BSMCAPRUBJMWDF-KRWDZBQOSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameCobimetinib
Pubchem CID16222100
DRUGBANK IDDB05239
Drug StatusAlone
Drug TypeSmall Molecule


Drug Targets:

MAP2K1 (Q02750)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 4
5604 MAP2K1 24
673 BRAF 91
Showing 1 to 3 of 3 rows

Gene in drug-gene network: Network Plot

Models in Cobimetinib

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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