iGMDRD557

Canonical SMILES: CN1C=C(N=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=CC=C5)F

InChI: InChI=1S/C26H20FN5O2S2/c1-32-14-20(29-15-32)23-13-19-25(36-23)22(9-10-28-19)34-21-8-7-17(12-18(21)27)30-26(35)31-24(33)11-16-5-3-2-4-6-16/h2-10,12-15H,11H2,1H3,(H2,30,31,33,35)

InChI Key: UFICVEHDQUKCEA-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameMGCD-265
Pubchem CID24901700
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: undefined model num: 1BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 1LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 3

Drug-gene pathway enrichments

3reactome: Signal Transduction2reactome: Pre-NOTCH Expression and Processing2reactome: Pre-NOTCH Transcription and Translation2reactome: Cell Cycle2wikipathways: Apoptosis Modulation and Signaling2reactome: Signaling by NOTCH2reactome: Cell Cycle, Mitotic2reactome: G1/S Transition2reactome: G1/S-Specific Transcription2kegg: MicroRNAs in cancer - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
4170 MCL1 2
8682 PEA15 1
1869 E2F1 1
Showing 1 to 3 of 3 rows

Gene in drug-gene network: Network Plot

Models in MGCD-265

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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