iGMDRD565

Canonical SMILES: CC1C(=O)N(C2=CN=C(N=C2N1CCC(C)C)NC3=CC(=C(C(=C3)F)O)F)C

InChI: InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24)

InChI Key: DTEKTGDVSARYDS-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameBI-D1870
CHEMBLCHEMBL573107
Pubchem CID25023700
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 4

Drug-gene pathway enrichments

5reactome: Signal Transduction4wikipathways: Notch Signaling Pathway4reactome: Generic Transcription Pathway4reactome: RNA Polymerase II Transcription4reactome: Transcriptional regulation by RUNX34reactome: Gene expression (Transcription)3reactome: Signaling by NOTCH13reactome: NOTCH1 Intracellular Domain Regulates Transcription3kegg: Pathways in cancer - Homo sapiens (human)3kegg: Breast cancer - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 1
4851 NOTCH1 1
4609 MYC 1
5624 PROC 1
Showing 1 to 4 of 4 rows

Gene in drug-gene network: Network Plot

Models in BI-D1870

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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