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iGMDRD65

Canonical SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O

InChI: InChI=1S/C27H29NO10/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3/t10-,14-,16-,17-,22+,27-/m0/s1

InChI Key: STQGQHZAVUOBTE-VGBVRHCVSA-N

Standard Name	CHEMBL	Pubchem CID	KEGG Drug ID	DRUGBANK ID	Drug Status	Drug targets (TTD)	Drug Type
Daunorubicin	CHEMBL178	30323	D07776	DB00694	Alone	DNC000517	Small Molecule

Drug Class:

Anthracycline Topoisomerase Inhibitor Anthracyclines Anthracyclines and Related Substances Antibiotics, Antineoplastic Antineoplastic Agents Antineoplastic and Immunomodulating Agents BCRP/ABCG2 Substrates Carbohydrates Cardiotoxic antineoplastic agents Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Cytotoxic Antibiotics and Related Substances Enzyme Inhibitors Glycosides Hydrocarbons Hydrocarbons, Aromatic Hydrocarbons, Cyclic Immunosuppressive Agents Myelosuppressive Agents Naphthacenes P-glycoprotein/ABCB1 Inducers P-glycoprotein/ABCB1 Inhibitors P-glycoprotein/ABCB1 Substrates Polycyclic Compounds Polycyclic Hydrocarbons, Aromatic Topoisomerase II Inhibitors Topoisomerase Inhibitors

Drug Targets:

DNA TOP2A (P11388)TOP2B (Q02880)

Drug Pathways:

Biosynthesis of type II polyketide products Biosynthesis of antibiotics

Drug Synonyms:

Daunorubicin (INN)DM DaunoXome (TN)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
2322	FLT3	2
4869	NPM1	3
7490	WT1	1
1788	DNMT3A	3
4297	KMT2A	1

Gene in drug-gene network: Network Plot

Models in Daunorubicin

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CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.