iGMDRD650
Canonical SMILES: CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F
InChI: InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)
InChI Key: UZWDCWONPYILKI-UHFFFAOYSA-N
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Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
Standard NameAbemaciclib CHEMBLCHEMBL3301610 Pubchem CID46220500 DRUGBANK IDDB12001 Drug StatusAlone Drug TypeSmall Molecule | |||||
Drug Class:
AminesBCRP/ABCG2 InhibitorsBCRP/ABCG2 SubstratesHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHeterocyclic Compounds, 2-RingKinase InhibitorP-glycoprotein/ABCB1 InhibitorsP-glycoprotein/ABCB1 SubstratesPyridinesDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene in drug-gene network: Network Plot
Models in Abemaciclib
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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