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iGMDRD669

Canonical SMILES: C1=CC=C(C=C1)C(COC2=CC3=C(C=C2)NC(=O)N3)NC(=O)C4=CC=CN(C4=O)CC5=CC(=C(C=C5)F)F

InChI: InChI=1S/C28H22F2N4O4/c29-21-10-8-17(13-22(21)30)15-34-12-4-7-20(27(34)36)26(35)31-25(18-5-2-1-3-6-18)16-38-19-9-11-23-24(14-19)33-28(37)32-23/h1-14,25H,15-16H2,(H,31,35)(H2,32,33,37)/t25-/m0/s1

InChI Key: GCWCGSPBENFEPE-VWLOTQADSA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
PDK1 inhibitor	CHEMBL1234429	49766500	Alone	Small Molecule

Drug Class:

Kinase Inhibitor Protein Kinase Inhibitors Antineoplastic Agents Antineoplastic Agents, Phytogenic

Drug Targets:

PDPK1 (PDK1)

Drug Pathways:

Other, kinases

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
4771	NF2	2
9757	KMT2B	2
8452	CUL3	1
1029	CDKN2A	1
7157	TP53	2
54894	RNF43	1
54880	BCOR	1
4763	NF1	1

Gene in drug-gene network: Network Plot

Models in PDK1 inhibitor

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.