iGMDRD674

Canonical SMILES: CN1CCN(CC1)C2=CC3=C(C=C2)NC(=C4C(=C5C(=NC4=O)C=CC=C5F)N)N3

InChI: InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11,24-25H,7-10,23H2,1H3

InChI Key: KCOYQXZDFIIGCY-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameDovitinib
CHEMBLCHEMBL522892 CHEMBL2103806
Pubchem CID49830600
Drug StatusAlone
Drug TypeSmall Molecule

Drug Class:

Kinase inhibitor

Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Invasive Breast Carcinoma (BRCA) model num: 2BREASTtissue: BREAST cancer: Breast Carcinoma model num: 4UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: Endometrial Carcinoma (UCEC) model num: 8BLADDEtissue: BLADDE cancer: BLADDER model num: 0BLADDERtissue: BLADDER cancer: Bladder Cancer model num: 2

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2249 FGF4 2
2248 FGF3 2
2260 FGFR1 2
2263 FGFR2 9
Showing 1 to 4 of 5 rows

Gene in drug-gene network: Network Plot

Models in Dovitinib

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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