iGMDRD83

Canonical SMILES: CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)O

InChI: InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1

InChI Key: GAGWJHPBXLXJQN-UORFTKCHSA-N

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Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard NameCapecitabine
CHEMBLCHEMBL1773
Pubchem CID60953
KEGG Drug IDD01223
DRUGBANK IDDB01101
Drug StatusAlone
Drug targets (TTD)DAP000761
Drug TypeSmall Molecule


Drug Targets:

TYMS (P04818)DNARNA


Drug-model tissue-cancer distribution: Bubble Plot

OTHEtissue: OTHE cancer: OTHER model num: 0OTHERtissue: OTHER cancer: Cancer of Unknown Primary (CUP) model num: 7BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: Colorectal Cancer model num: 3BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Breast Carcinoma model num: 2

Drug-gene pathway enrichments

6reactome: Signal Transduction4reactome: Signaling by Receptor Tyrosine Kinases3kegg: Breast cancer - Homo sapiens (human)3kegg: Gastric cancer - Homo sapiens (human)3wikipathways: Bladder Cancer3kegg: Non-small cell lung cancer - Homo sapiens (human)3kegg: Bladder cancer - Homo sapiens (human)3reactome: PIP3 activates AKT signaling3reactome: Intracellular signaling by second messengers3kegg: MAPK signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

8CC: cytosol5MF: dihydropyrimidine dehydrogenase (NADP+) activity5CC: plasma membrane4MF: protein binding4MF: protein tyrosine kinase activity4CC: cytoplasm4CC: nucleus4MF: identical protein binding4BP: positive regulation of gene expression4MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2064 ERBB2 3
7157 TP53 1
673 BRAF 1
1806 DPYD 7
Showing 1 to 4 of 4 rows

Gene in drug-gene network: Network Plot

Models in Capecitabine

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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