iGMDRD835

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Standard Name
Drug Status
Drug Type
Standard NameBET inhibitor
Drug StatusFamily
Drug Typeundefined

Drug-model tissue-cancer distribution: Bubble Plot

HEAD_NECtissue: HEAD_NEC cancer: HEAD_NECK model num: 0HEAD_NECKtissue: HEAD_NECK cancer: NUT Midline Carcinoma of the Head and Neck (NMCHN) model num: 2HEAD_NECKtissue: HEAD_NECK cancer: Head and Neck Squamous Cell Carcinoma (HNSC) model num: 1HEAD_NECKtissue: HEAD_NECK cancer: Head and Neck Carcinoma, Other (OHNCA) model num: 1BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: Acute Lymphoid Leukemia (ALL) model num: 2BLOODtissue: BLOOD cancer: Acute Myeloid Leukemia (AML) model num: 2BLOODtissue: BLOOD cancer: Multiple Myeloma (MM) model num: 3LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: Lung Cancer model num: 4BRAItissue: BRAI cancer: BRAIN model num: 0BRAINtissue: BRAIN cancer: Neuroblastoma (NBL) model num: 3OTHEtissue: OTHE cancer: OTHER model num: 0OTHERtissue: OTHER cancer: Cancer of Unknown Primary (CUP) model num: 3

Drug-gene pathway enrichments

6reactome: Generic Transcription Pathway6reactome: Gene expression (Transcription)6reactome: Signal Transduction6reactome: RNA Polymerase II Transcription3kegg: PI3K-Akt signaling pathway - Homo sapiens (human)3wikipathways: PI3K-Akt Signaling Pathway3netpath: EGFR13wikipathways: Integrated Breast Cancer Pathway2reactome: Signaling by NTRKs2reactome: Diseases of signal transduction

Drug-gene GO enrichments

8CC: nucleus7CC: nucleoplasm6MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding6MF: protein binding5CC: cytosol5BP: positive regulation of transcription by RNA polymerase II3BP: positive regulation of gene expression3BP: positive regulation of transcription, DNA-templated3BP: cell cycle arrest3BP: positive regulation of cell proliferation

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 2
2195 FAT1 2
6794 STK11 2
4609 MYC 6
Showing 1 to 4 of 6 rows

Gene in drug-gene network: Network Plot

Models in BET inhibitor

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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