NT5C2
Summary: This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:600417 Ensembl IDEnsembl:ENSG00000076685 HGNC IDHGNC:HGNC:8022 PHARMGKB IDPA31801 Map Location10q24.32-q24.33 | |||||
GO terms in NT5C2
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0000166 | nucleotide binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | EXP | GO:0008253 | 5'-nucleotidase activity |
| MF | IBA | GO:0008253 | 5'-nucleotidase activity |
| MF | IEA | GO:0046872 | metal ion binding |
| MF | TAS | GO:0050146 | nucleoside phosphotransferase activity |
Gene expression in normal tissue: NT5C2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NT5C2
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-15869 | Metabolism of nucleotides |
| reactome | R-HSA-2161522 | Abacavir transport and metabolism |
| reactome | R-HSA-2161541 | Abacavir metabolism |
| reactome | R-HSA-74259 | Purine catabolism |
| reactome | R-HSA-8956319 | Nucleobase catabolism |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NT5C2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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