ETV4


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
ETS variant 4MIM:600711Ensembl:ENSG00000175832HGNC:HGNC:3493PA2790717q21.31

Gene Categories:

CLINICALLY ACTIONABLE

GO terms in ETV4


Term TypeEvidence TypeGO Term IDGO Des.
MFIDAGO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
MFIBAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISMGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFNASGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFICGO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
MFIPIGO:0005515protein binding
BPIBAGO:0006357regulation of transcription by RNA polymerase II
BPIEAGO:0006366transcription by RNA polymerase II
BPIBAGO:0030154cell differentiation
BPIDAGO:0045944positive regulation of transcription by RNA polymerase II
CCIBAGO:0005634nucleus
CCTASGO:0005654nucleoplasm
CCIDAGO:0005730nucleolus

Gene expression in normal tissue: ETV4

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ETV4


DatabasePathway IDPathway Des.
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-5683057MAPK family signaling cascades
reactomeR-HSA-5687128MAPK6/MAPK4 signaling
wikipathwaysWP2263Androgen Receptor Network in Prostate Cancer
kegghsa05202Transcriptional misregulation in cancer - Homo sapiens (human)
pidlkb1_pathwayLKB1 signaling events

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012
iGMDRD434BMS-5369243
iGMDRD577BIX012943
iGMDRD399Selumetinib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ETV4

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