RBM10


Summary: This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
RNA binding motif protein 10MIM:300080Ensembl:ENSG00000182872HGNC:HGNC:9896PA34259Xp11.3

GO terms in RBM10


Term TypeEvidence TypeGO Term IDGO Des.
CCIDAGO:0005634nucleus
CCIDAGO:0016607nuclear speck
BPIEAGO:0000381regulation of alternative mRNA splicing, via spliceosome
BPIEAGO:0006397mRNA processing
BPNDGO:0008150biological_process
BPIEAGO:0008380RNA splicing
BPIEAGO:0042981regulation of apoptotic process
MFHDAGO:0003723RNA binding
MFIPIGO:0005515protein binding
MFIDAGO:0035198miRNA binding
MFIPIGO:0042802identical protein binding
MFIDAGO:0044877protein-containing complex binding
MFIEAGO:0046872metal ion binding

Gene expression in normal tissue: RBM10

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RBM10


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD546BMS-7548071
iGMDRD462OSI-906 (Linsitinib)1
iGMDRD353PD03259011
iGMDRD399Selumetinib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RBM10

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