STK35
Summary: The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| serine/threonine kinase 35 | MIM:609370 | Ensembl:ENSG00000125834 | HGNC:HGNC:16254 | PA38097 | 20p13 |
GO terms in STK35
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004672 | protein kinase activity |
| MF | IEA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
| CC | IEA | GO:0005730 | nucleolus |
| CC | IEA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0016604 | nuclear body |
| BP | IEA | GO:0006468 | protein phosphorylation |
| BP | IBA | GO:0051321 | meiotic cell cycle |
Gene expression in normal tissue: STK35
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in STK35
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD187 | BRD9876 | 2 |
| iGMDRD451 | Serdemetan | 3 |
| iGMDRD513 | BML-259 | 3 |
| iGMDRD100 | Zebularine | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in STK35
CLASSFICATION
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