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ZNF638

Summary: The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
zinc finger protein 638	MIM:614349	Ensembl:ENSG00000075292	HGNC:HGNC:17894	PA134983478	2p13.3-p13.2

GO terms in ZNF638

Term Type	Evidence Type	GO Term ID	GO Des.
MF	TAS	GO:0003690	double-stranded DNA binding
MF	HDA	GO:0003723	RNA binding
MF	IEA	GO:0008270	zinc ion binding
BP	IEA	GO:0006351	transcription, DNA-templated
BP	IEA	GO:0006355	regulation of transcription, DNA-templated
BP	IEA	GO:0008380	RNA splicing
CC	IDA	GO:0005654	nucleoplasm
CC	TAS	GO:0005737	cytoplasm
CC	IEA	GO:0016607	nuclear speck
CC	IDA	GO:0043231	intracellular membrane-bounded organelle

Gene expression in normal tissue: ZNF638

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ZNF638

Database	Pathway ID	Pathway Des.
reactome	R-HSA-1266738	Developmental Biology
reactome	R-HSA-381340	Transcriptional regulation of white adipocyte differentiation

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD686	PF4708671	1
iGMDRD749	ZINC6718453	1
iGMDRD66	Doxorubicin	1
iGMDRD605	AZD6482	1
iGMDRD372	TGX 221	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ZNF638

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DATATYPES

CLASSFICATION

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