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iGMDRD127

Canonical SMILES: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C

InChI: InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1

InChI Key: BTIHMVBBUGXLCJ-OAHLLOKOSA-N

Standard Name	CHEMBL	Pubchem CID	DRUGBANK ID	Drug Status	Drug Type
Seliciclib	CHEMBL14762	160355	DB06195	Alone	Small Molecule

Drug Class:

Antineoplastic Agents COX Inhibitors COX-2 Inhibitors Cyclin-Dependent Kinases, antagonists & inhibitors Enzyme Inhibitors Heterocyclic Compounds Heterocyclic Compounds, 2-Ring Protein Kinase Inhibitors

Drug Targets:

CDK1 (P06493)CDK2 (P24941)MAPK3 (P27361)MAPK1 (P28482)CDK7 (P50613)CDK9 (P50750)CSNK1E (P49674)

Drug Pathways:

Cell cycle

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
9757	KMT2B	1
1387	CREBBP	1
8242	KDM5C	1
6416	MAP2K4	1
3932	LCK	1
162979	ZNF296	2
5728	PTEN	1

Gene in drug-gene network: Network Plot

Models in Seliciclib

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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.