iGMDRD162

Canonical SMILES: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C

InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+

InChI Key: SHGAZHPCJJPHSC-YCNIQYBTSA-N

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Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug Type
Standard NameAll-trans Retinoic Acid
CHEMBLCHEMBL38
Pubchem CID444795
KEGG Drug IDD00094
DRUGBANK IDDB00755
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

RARARARBRARG


Drug-model tissue-cancer distribution: Bubble Plot

BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: Acute Myeloid Leukemia (AML) model num: 5BLOODtissue: BLOOD cancer: Leukemia (LEUK) model num: 7HEAD_NECtissue: HEAD_NEC cancer: HEAD_NECK model num: 0HEAD_NECKtissue: HEAD_NECK cancer: Head and Neck Squamous Cell Carcinoma (HNSC) model num: 1

Drug-gene pathway enrichments

3kegg: Pathways in cancer - Homo sapiens (human)3reactome: Signal Transduction3kegg: Acute myeloid leukemia - Homo sapiens (human)3kegg: Transcriptional misregulation in cancer - Homo sapiens (human)2reactome: Metabolism of proteins2reactome: Transcriptional Regulation by TP532reactome: Generic Transcription Pathway2reactome: Post-translational protein modification2reactome: SUMO E3 ligases SUMOylate target proteins2reactome: Gene expression (Transcription)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
8854 ALDH1A2 1
1050 CEBPA 1
2322 FLT3 2
4869 NPM1 3
Showing 1 to 4 of 5 rows

Gene in drug-gene network: Network Plot

Models in All-trans Retinoic Acid

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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