iGMDRD514

Canonical SMILES: CCOC1=CC=C(/C=C2SC(N(CCN)C\2=O)=O)C=C1.Cl

InChI: InChI=1S/C14H16N2O3S.ClH/c1-2-19-11-5-3-10(4-6-11)9-12-13(17)16(8-7-15)14(18)20-12;/h3-6,9H,2,7-8,15H2,1H3;1H/b12-9-;InChI=1S/C14H16N2O3S.ClH/c1-2-19-11-5-3-10(4-6-11)9-12-13(17)16(8-7-15)14(18)20-12;/h3-6,9H,2,7-8,15H2,1H3;1H/b12-9-;

InChI Key: PQVLWVGMXJPJLG-MWMYENNMSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameERK inhibitor
Pubchem CID16760400
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

8reactome: Signal Transduction6reactome: Signaling by Receptor Tyrosine Kinases5kegg: Gastric cancer - Homo sapiens (human)5kegg: Hepatocellular carcinoma - Homo sapiens (human)5kegg: Breast cancer - Homo sapiens (human)5wikipathways: Signaling Pathways in Glioblastoma5pid: PDGFR-beta signaling pathway5reactome: Signaling by NTRKs5reactome: Disease5pid: mTOR signaling pathway

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 2
5605 MAP2K2 5
5604 MAP2K1 10
673 BRAF 4
Showing 1 to 4 of 5 rows

Gene in drug-gene network: Network Plot

Models in ERK inhibitor

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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