iGMDRD632

Canonical SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)N3C(=NC(=N3)C4=CC=CC=N4)N)OC

InChI: InChI=1S/C17H15N7O2/c1-25-13-7-10-12(8-14(13)26-2)20-9-21-16(10)24-17(18)22-15(23-24)11-5-3-4-6-19-11/h3-9H,1-2H3,(H2,18,22,23)

InChI Key: ILBRKJBKDGCSCB-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameCP466722
CHEMBLCHEMBL2143829
Pubchem CID44551700
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

ATM

Drug Pathways:

Genome integrity

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 3BONtissue: BON cancer: BONE model num: 0BONEtissue: BONE cancer: Acute Myeloid Leukemia (AML) model num: 2LYMPtissue: LYMP cancer: LYMPH model num: 0LYMPHtissue: LYMPH cancer: Diffuse Large B-Cell Lymphoma (DLBCL) model num: 1

Drug-gene pathway enrichments

7reactome: Signal Transduction4reactome: Signaling by Receptor Tyrosine Kinases4reactome: Developmental Biology3reactome: VEGFA-VEGFR2 Pathway3reactome: Gene expression (Transcription)3reactome: Signaling by VEGF2kegg: Pathways in cancer - Homo sapiens (human)2kegg: Viral carcinogenesis - Homo sapiens (human)2kegg: Kaposi,s sarcoma-associated herpesvirus infection - Homo sapiens (human)2kegg: HTLV-I infection - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
1387 CREBBP 2
3791 KDR 1
23380 SRGAP2 1
4893 NRAS 2
Showing 1 to 4 of 5 rows

Gene in drug-gene network: Network Plot

Models in CP466722

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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