CMC4
Summary: This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the downstream 8 kDa protein that localizes to mitochondria.[provided by RefSeq, Mar 2009].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
C-X9-C motif containing 4 | Ensembl:ENSG00000182712 | HGNC:HGNC:35428 | PA164723191 | Xq28 |
GO terms in CMC4
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | TAS | GO:0008283 | cell proliferation |
CC | IDA | GO:0005739 | mitochondrion |
CC | IBA | GO:0005758 | mitochondrial intermembrane space |
Gene expression in normal tissue: CMC4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CMC4
Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-1268020 | Mitochondrial protein import |
reactome | R-HSA-392499 | Metabolism of proteins |
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD307 | Manumycin A | 6 |
iGMDRD888 | Compound 44 | 12 |
iGMDRD297 | Austocystin D | 6 |
iGMDRD64 | Parbendazole | 6 |
iGMDRD280 | CYTOCHALASIN B | 10 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CMC4