iGMDRD106

Canonical SMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(N=C2N)Cl

InChI: InChI=1S/C10H11ClFN5O3/c11-10-15-7(13)5-8(16-10)17(2-14-5)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4+,6-,9-/m1/s1

InChI Key: WDDPHFBMKLOVOX-AYQXTPAHSA-N

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Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard NameClofarabine
CHEMBLCHEMBL1750
Pubchem CID119182
KEGG Drug IDD03546
DRUGBANK IDDB00631
Drug StatusAlone
Drug targets (TTD)DAP000849
Drug TypeSmall Molecule




Drug-model tissue-cancer distribution: Bubble Plot

SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: undefined model num: 1PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: undefined model num: 1LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 2undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 8

Drug-gene pathway enrichments

4reactome: Signal Transduction3reactome: Cell Cycle, Mitotic3reactome: Cell Cycle2reactome: G0 and Early G12reactome: G1/S-Specific Transcription2reactome: Disease2reactome: Activation of E2F1 target genes at G1/S2reactome: Signaling by NOTCH2reactome: Mitotic G1-G1/S phases2reactome: Pre-NOTCH Expression and Processing

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 1
2956 MSH6 1
1869 E2F1 1
11315 PARK7 1
Showing 1 to 4 of 5 rows

Gene in drug-gene network: Network Plot

Models in Clofarabine

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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