iGMDRD170

Canonical SMILES: CC(C)N1C2=CC=CC=C2C(=C1C=CC(CC(CC(=O)O)O)O)C3=CC=C(C=C3)F

InChI: InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m1/s1

InChI Key: FJLGEFLZQAZZCD-MCBHFWOFSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameFluvastatin
CHEMBLCHEMBL350239
Pubchem CID446155
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

HMGCR

Drug Pathways:

Bile secretion

Drug-model tissue-cancer distribution: Bubble Plot

LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 11

Drug-gene pathway enrichments

4reactome: Signal Transduction3kegg: PI3K-Akt signaling pathway - Homo sapiens (human)3kegg: MicroRNAs in cancer - Homo sapiens (human)3reactome: Signaling by Receptor Tyrosine Kinases2netpath: EGFR12reactome: Disease2reactome: PIP3 activates AKT signaling2reactome: YAP1- and WWTR1 (TAZ)-stimulated gene expression2reactome: RNA Polymerase II Transcription2kegg: MAPK signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
10987 COPS5 1
4170 MCL1 1
5159 PDGFRB 1
25937 WWTR1 1
Showing 1 to 4 of 6 rows

Gene in drug-gene network: Network Plot

Models in Fluvastatin

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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