iGMDRD184

Canonical SMILES: C1=CC=C2C(=C1)C=CC(=C2SSC3=C(C=CC4=CC=CC=C43)O)O

InChI: InChI=1S/C20H14O2S2/c21-17-11-9-13-5-1-3-7-15(13)19(17)23-24-20-16-8-4-2-6-14(16)10-12-18(20)22/h1-12,21-22H

InChI Key: RFAXLXKIAKIUDT-UHFFFAOYSA-N

Loading, please wait...
Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameIPA-3
CHEMBLCHEMBL472940
Pubchem CID521106
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

PAK1PAK2PAK3

Drug Pathways:

Cytoskeleton

Drug-model tissue-cancer distribution: Bubble Plot

BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 17LYMPtissue: LYMP cancer: LYMPH model num: 0LYMPHtissue: LYMPH cancer: Diffuse Large B-Cell Lymphoma (DLBCL) model num: 1

Drug-gene pathway enrichments

8reactome: Signal Transduction7reactome: Signaling by Receptor Tyrosine Kinases4reactome: PI3K/AKT Signaling in Cancer4reactome: Constitutive Signaling by Aberrant PI3K in Cancer4reactome: MAPK family signaling cascades4reactome: Generic Transcription Pathway4reactome: Diseases of signal transduction4reactome: Negative regulation of the PI3K/AKT network4reactome: Signaling by ERBB24reactome: SHC1 events in ERBB2 signaling

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
2064 ERBB2 1
983 CDK1 1
29760 BLNK 1
3932 LCK 1
Showing 1 to 4 of 8 rows

Gene in drug-gene network: Network Plot

Models in IPA-3

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.