iGMDRD582

Canonical SMILES: B(C(CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O

InChI: InChI=1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1

InChI Key: MXAYKZJJDUDWDS-LBPRGKRZSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameMLN 2238
CHEMBLCHEMBL2141296
Pubchem CID25183900
DRUGBANK IDDB09570
Drug StatusAlone
Drug TypeSmall Molecule


Drug Targets:

PSMB5

Drug-model tissue-cancer distribution: Bubble Plot

OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 7BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: Colorectal Cancer model num: 1

Drug-gene pathway enrichments

5reactome: Signal Transduction3kegg: HTLV-I infection - Homo sapiens (human)3wikipathways: EGF-EGFR Signaling Pathway2reactome: Signaling by NTRK1 (TRKA)2kegg: Hepatitis B - Homo sapiens (human)2kegg: Human papillomavirus infection - Homo sapiens (human)2reactome: Mismatch Repair2reactome: Metabolism of proteins2kegg: Insulin signaling pathway - Homo sapiens (human)2reactome: Generic Transcription Pathway

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 1
3845 KRAS 1
1978 EIF4EBP1 1
7301 TYRO3 1
Showing 1 to 4 of 5 rows

Gene in drug-gene network: Network Plot

Models in MLN 2238

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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